Starter 785 nm: 300-3300 cm-1 Base model 532 nm: 100-4350* cm-1 Base model 785 nm: 100-3425* cm-1 Base model 1000 nm: 200-2400 cm-1 Hybrid 785 nm: 150-1890** cm-1 *Low signal-to-noise ratio at <150 cm-1 **Low signal-to-noise ratio at <175 cm-1
Adeptly harness the power of Raman spectroscopy with the Raman Rxn2 analyzer. Designed for use in analytical laboratories with model transfer capabilities, the Raman Rxn2 is heavily relied on for routine sample identification, support of R&D projects, early process development, and scale-up settings for in situ analysis. Available as a benchtop or on a mobile wheeled cart, the Raman Rxn2 offers location convenience and portability for process development laboratories.
Borealis is monitoring of polypropylene and polyethylene grades during olefin polymerization reactions in continuously fed loop reactors in the Chemical Industry.
KBI Biopharma is monitoring a diverse array of cell lines and cell concentrations in minimal volume for automated cell cultivation in the Life Sciences industry.
Raman downstream process measurement of biosimilars - Alvotech’s testing of the protein purification process during ultrafiltration/diafiltration (UF/DF)
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
Starter 785 nm: 300-3300 cm-1 Base model 532 nm: 100-4350* cm-1 Base model 785 nm: 100-3425* cm-1 Base model 1000 nm: 200-2400 cm-1 Hybrid 785 nm: 150-1890** cm-1 *Low signal-to-noise ratio at <150 cm-1 **Low signal-to-noise ratio at <175 cm-1
Spectral resolution
Starter: 10 cm-1 (average) Base model (average): 5 cm-1 (532 nm) 4 cm-1 (785 nm) 6 cm-1 (1000 nm) Hybrid: 4 cm-1 (785 nm) average
Channels
Starter: Single channel Base Model: Up to four channels Hybrid: Up to two channels
Ambient temperature
Operating: 15 to 30 °C 59 to 86 °F Storage: -15 to 50 °C 5 to 122 °F
Starter 785 nm: 300-3300 cm-1 Base model 532 nm: 100-4350* cm-1 Base model 785 nm: 100-3425* cm-1 Base model 1000 nm: 200-2400 cm-1 Hybrid 785 nm: 150-1890** cm-1 *Low signal-to-noise ratio at <150 cm-1 **Low signal-to-noise ratio at <175 cm-1
Spectral resolution
Starter: 10 cm-1 (average) Base model (average): 5 cm-1 (532 nm) 4 cm-1 (785 nm) 6 cm-1 (1000 nm) Hybrid: 4 cm-1 (785 nm) average
Channels
Starter: Single channel Base Model: Up to four channels Hybrid: Up to two channels
Ambient temperature
Operating: 15 to 30 °C 59 to 86 °F Storage: -15 to 50 °C 5 to 122 °F
Raman downstream process measurement of biosimilars -
Alvotech's monitoring of the protein purification process
during ultrafiltration / diafiltration (UF/DF)
English version - 06/2024
New version available in English
This case study examines Alvotech's use of Raman systems
(Raman Rxn2 analyzer with Rxn-10 probe and Raman flow assembly)
to monitor the downstream protein purification process during UF/DF.
